Microbial metabolites with inhibitory activity against lipid metabolism
نویسندگان
چکیده
منابع مشابه
Microbial metabolites affecting lipid biosynt hesis
Microbial inhibitors for two enzymes involved in lipid metabolism, acylCoA:cholesterol acyltransferase (ACAT) and famesyl-protein transferase (FTase), were screened with assay systems using partially purified enzymes. ACAT inhibitors are expected to work as cholesterol-lowering or anti-atherosclerotic agents, and FTase inhibitors are as anticancer drugs. Three kinds of new ACAT inhibitors were ...
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H EMOSTATIC DISORDERS with a varying incidence of bleeding, are common in the dysproteinemias, and are characteristic of the macroglobulinemia of \\Taldenstr#{246}m These abnormalities are most frequently attributed to abnormal platelet function,1 and depression of specific clotting factors appears to be a rare occurrence. Nilehn2 includes four instances of antihemophilic globulin ( factor VIII...
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ژورنال
عنوان ژورنال: Proceedings of the Japan Academy, Series B
سال: 2002
ISSN: 0386-2208,1349-2896
DOI: 10.2183/pjab.78.217